Preconditioning preserves sarcoplasmic reticular function

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Ischemic preconditioning preserves mitochondrial function after global cerebral ischemia in rat hippocampus.

Ischemic tolerance in brain develops when sublethal ischemic insults occur before "lethal" cerebral ischemia. Two windows for the induction of tolerance by ischemic preconditioning (IPC) have been proposed: one that occurs within 1 hour after IPC, and another that occurs 1 or 2 days after IPC. The authors tested the hypotheses that IPC would reduce or prevent ischemia-induced mitochondrial dysf...

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and motor function . preserves

Oxidative damage has been suggested as a potential mechanism for both atherosclerosis and neurodegenerative disorders such as Parkinson's disease.' One report has noted a 2-5-fold increased risk of cardiovascular disease among patients with Parkinson's disease,2 suggesting that a common genetic variant may contribute to both diseases. One such candidate genetic factor, the ApoE-E4 allele, is fo...

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Hepatic preconditioning preserves energy metabolism during sustained ischemia.

We evaluated the possibility that ischemic preconditioning could modify hepatic energy metabolism during ischemia. Accordingly, high-energy nucleotides and their degradation products, glycogen and glycolytic intermediates and regulatory metabolites, were compared between preconditioned and nonpreconditioned livers. Preconditioning preserved to a greater extent ATP, adenine nucleotide pool, and ...

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Ischemic preconditioning preserves creatine phosphate and intracellular pH.

BACKGROUND Ischemic preconditioning slows ATP depletion and ultrastructural damage during the final episode of ischemia. To define the influence of creatine phosphate (CP) and intracellular pH (pHi) on this effect, CP and pHi were serially measured in porcine hearts without collateral circulation by using 31P-NMR spectroscopy and ultrastructural examination. METHODS AND RESULTS Farm pigs weig...

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and motor function . preserves sensory

Oxidative damage has been suggested as a potential mechanism for both atherosclerosis and neurodegenerative disorders such as Parkinson's disease.' One report has noted a 2-5-fold increased risk of cardiovascular disease among patients with Parkinson's disease,2 suggesting that a common genetic variant may contribute to both diseases. One such candidate genetic factor, the ApoE-E4 allele, is fo...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 1996

ISSN: 0735-1097

DOI: 10.1016/s0735-1097(96)81585-3